已发表论文：（*为通讯作者） (1) Da Zhang*#, Chenwei Jiang#, Xiaoyuan Zheng#, Zhiwen Lin#, Qiuyu Zhuang, Huanzhang Xie, Yuzhi Liang, Yu Xu, Linsheng Cui, Xiaolong Liu*, Yongyi Zeng*. Normalization of Tumor Vessels by Lenvatinib-Based Metallo-Nanodrugs Alleviates Hypoxia and Enhances Calreticulin-Mediated Immune Responses in Orthotopic HCC and Organoids. Small (2023): 2207786 (IF: 15.153, 一区) (2) Ming Wu#, Hao Li#, Cao Zhang, Yingchao Wang, Cuilin Zhang, Yuting Zhang, Aoxue Zhong, Da Zhang*, Xiaolong Liu*. Silk-Gel Powered Adenoviral Vector Enables Robust Genome Editing of PD-L1 to Augment Immunotherapy across Multiple Tumor Models. Advanced Science (2023): 2206399. (IF: 17.521, 一区) (3) Qingfu Zhao#, Yunhao Wang#, Binyu Zhao#, Hengkai Chen, Zhixiong Cai, Youshi Zheng, Yongyi Zeng, Da Zhang*, and Xiaolong Liu* Neoantigen Immunotherapeutic-Gel Combined with TIM-3 Blockade Effectively Restrains Orthotopic Hepatocellular Carcinoma Progression. Nano Lett. 2022. 9;22(5):2048-2058. (IF: 11.189, 一区, TOP) (4) [2] Yunhao Wang#, Qingfu Zhao#, Binyu Zhao, Youshi Zheng, Qiuyu Zhuang, Naishun Liao, Peiyuan Wang, Zhixiong Cai, Da Zhang*, Yongyi Zeng*, Xiaolong Liu*. Remodeling Tumor-Associated Neutrophils to Enhance Dendritic Cell-Based HCC Neoantigen Nano-Vaccine Efficiency. Advanced Science. 2022, 2105631. (IF: 17.521, 一区) (5) Zhijin Fan, Cheng Jiang, Yichao Wang, Kaiyuan Wang, Jade Marsh, Da Zhang*, Xin Chen*, Liming Nie* Engineered Extracellular Vesicles as Intelligent Nanosystem for Next-Generation of Nanomedicine, Nanoscale Horiz, 2022,7, 682-714. (IF: 11.684, 一区) (6) [Da Zhang#, Tianhong Teng#, Qingfu Zhao#, Zhiwen Lin, Junrong Zhang, Xiaolong Liu, and Yongyi Zeng* Nanoparticles for Near-Infrared Light-Driven Singlet Oxygen and CO Gas Cogeneration for Pancreatic Adenocarcinoma Therapy, ACS Appl. Nano Mater. 2022, 5, 11, 16741–16752 (IF: 6.1, 二区) (7) Da Zhang#, Youshi Zheng#, Ziguo Lin, Xiaolong Liu, Juan Li*, Huanghao Yang*, Weihong Tan. Equipping Natural Killer Cells with Specific Targeting and Checkpoint Blocking for Enhanced Adoptive Immunotherapy in Solid Tumors. Angew Chem Int Ed Engl.2020.59,12022-12028. (IF: 16.823, 一区, TOP) (8) Da Zhang#, Ziguo Lin#, Ming Wu#, Zhixiong Cai, Youshi Zheng, Lei He, Zhenli Li, Jie Zhou, Liqin Sun, Geng Chen, Yongyi Zeng, Juan Li, Jingfeng Liu*, Huanghao Yang*, Xiaolong Liu*.Cytosolic Delivery of Thiolated Neoantigen Nano-vaccine Combined with Immune Checkpoint Blockade to Boost Anti-cancer T Cell Immunity. Advanced Science. 2021. 8, 2003504. (IF: 17.521, 一区) (9) Da Zhang#, Ziguo Lin#, Youshi Zheng, Jibin Song, Juan Li, Yongyi Zeng,* and Xiaolong Liu*. Ultrasound-Driven Biomimetic Nanosystem Suppresses Tumor Growth and Metastasis through Sonodynamic Therapy, CO Therapy, and Indoleamine 2,3-Dioxygenase Inhibition. ACS Nano, 2020. 14, 8985-8999. (IF: 18.027, 一区) (10) Chengyun Chen, Yuhong Tong, Youshi Zheng, Yingjun Shi, Zhaowei Chen, Juan Li, Xiaolong Liu, Da Zhang*, Huanghao Yang*. Cytosolic Delivery of Thiolated Mn-cGAMP Nanovaccine to Enhance the Antitumor Immune Responses. Small. 2021.2006970. (IF: 15.153, 一区) (11) Xianglian Liao, Youshi Zheng, Ziguo Lin, Yi Shen, Huiyun Lin, Xiaolong Liu, Da Zhang*, Buhong Li*. Self-assembled metallo-supramolecular nanoflowers for NIR / acidic-triggered multidrug release, long-term tumor retention and NIR-II fluorescence imaging-guided photo-chemotherapy. Chemical Engineering Journal. 2020. 400, 125882. (IF: 16.8, 一区) (12) Da Zhang#, Youshi Zheng#, Ziguo Lin, Shanyou Lan, Xiaolong Zhang, Aixian Zheng, Juan Li, Gang Liu, Huanghao Yang, Xiaolong Liu*, Jingfeng Liu*. Artificial Engineered Natural Killer Cells Combined with Antiheat Endurance as Powerful Strategy for Enhancing Photothermal- Immunotherapy Efficiency of Solid Tumors. Small. 2019. 15, 1970228. (IF: 15.153, 一区) (13) Da Zhang# , Cuilin Zhang# , Shanyou Lan, Yanbing Huang, Jingfeng Liu, Juan Li*, Xiaolong Liu*, Huanghao Yang* Near-Infrared Light Activated Thermosensitive Ion Channel to Remotely Control Transgene System for Thrombolysis Therapy. Small. 2019. 15, 1901176. (IF: 15.153, 一区) (14) Da Zhang#, Ming. Wu, Zhixiong Cai, Naishun Liao, Kun Ke, Hongzhi Liu, Ming Li, Gang Liu, Huanghao Yang, Xiaolong Liu* , Jingfeng Liu*. Chemotherapeutic Drug Based Metal–Organic Particles for Microvesicle-Mediated Deep Penetration and Programmable pH/NIR/Hypoxia Activated Cancer Photochemotherapy. Advanced Science, 2018. 5, 1700648. (IF: 17.521, 一区) (15) Da Zhang, Aixian Zheng, Juan Li, Ming Wu, Zhixiong Cai, Lingjie Wu, Zuwu Wei, Huanghao Yang, Gang Liu, Xiaolong Liu* , Jingfeng Liu*. Tumor Microenvironment Activable Self-Assembled DNA Hybrids for pH and Redox Dual-Responsive Chemotherapy / PDT Treatment of Hepatocellular Carcinoma, Advanced Science, 2017. 4, 1600460. (IF: 17.521, 一区) (16) Da Zhang, Aixian Zheng, Juan Li, Ming Wu, Lingjie Wu, Zuwu Wei, Naishun Liao, Xiaolong Zhang, Zhixiong Cai, Huanghao Yang, Gang Liu, Xiaolong Liu* , Jingfeng Liu*.Smart Cu(II)-aptamer complexes based gold nanoplatform for tumor micro-environment triggered programmable intracellular prodrug release, photodynamic treatment and aggregation induced photothermal therapy of hepatocellular carcinoma. Theranostics, 2017, 7,164-179. (IF: 11.556, 一区) (17) Da Zhang, Zhixiong Cai, Naishun Liao, Shanyou Lan, Ming Wu, Haiyan Sun, Zuwu Wei,Juan Li*, Xiaolong Liu*.pH / hypoxia programmable triggered cancer photo-chemotherapy based on a semiconducting polymer dot hybridized mesoporous silica framework. Chemical science, 2018. 9, 7390-7399. (IF: 9.825, 一区) (18) [Ming Wu#, Dongye Zheng#, Da Zhang #, Peiwen Yu, Lianli Peng, Feng Chen, Ziguo Lin,Zhixiong Cai, Jiong Li, Zuwu Wei, Xinyi Lin, Jingfeng Liu*, Xiaolong Liu*. Converting Immune Cold into Hot by Biosynthetic Functional Vesicles to Boost Systematic Antitumor Immunity. iScience, 2020. 23, 101341. (IF: 6.4, 二区) (19) Da Zhang, Ming Wu., Yongyi Zeng, Lingjie Wu, Qingtang Wang, Xiao Han, Xiaolong Liu*, Jingfeng Liu*.Chlorin e6 conjugated poly (dopamine) nanospheres as PDT / PTT dual-modal therapeutic agents for enhanced cancer therapy, ACS applied materials & interfaces, 2015. 7, 8176- 8187. (IF: 10.383, 二区) (20) Da Zhang, Hao Xu, Xiaolong Zhang, Yubin Liu, Ming Wu, Juan Li, Huanghao Yang, Gang Liu, Xiaolong Liu*, Jingfeng Liu*, Zhen Yuan. Self-Quenched Metal-Organic Particles as Dual-Mode Therapeutic Agents for Photoacoustic Imaging-Guided Second Near-Infrared Window Photochemotherapy. ACS applied materials & interfaces, 2018. 10, 25203-25212. (IF: 10.383, 二区) (21) Shanyou Lan, Ziguo Lin, Da Zhang*, Yongyi Zeng*, Xiaolong Liu. Photocatalysis Enhancement for Programmable Killing of Hepatocellular Carcinoma through Self-Compensation Mechanisms based on Black Phosphorus Quantum Dot hybridized Nanocatalysts, ACS applied materials & interfaces, 2019. 11, 9804-9813. (IF: 10.383, 二区) (22) Yanlin Du#, Da Zhang#, Yiru Wang, Ming Wu, Cuilin Zhang, Youshi Zheng, Aixian Zheng*, Xiaolong Liu*. A highly stable multifunctional aptamer for enhancing antitumor immunity against hepatocellular carcinoma by blocking dual immune checkpoints Biomaterials Science. 2021. 9, 4159-4168. (IF: 7.590, 二区) (23) Youshi. Zheng, Cuilin. Zhang, Zishen. Lai, Yongyi. Zeng, Juan. Li, Da. Zhang* and Xiaolong. Liu*, Redirecting natural killer cells to potentiate adoptive immunotherapy in solid tumors through stabilized Y-type bispecifific aptamer. Nanoscale, 2021.13,11279. (IF: 8.307, 二区) (24) Liao, Naishun#, Da Zhang#, Ming Wu, Huanghao Yang, Xiaolong Liu*, and Jibin Song*. Enhancing therapeutic effects and in vivo tracking of adipose tissue-derived mesenchymal stem cells for liver injury using bioorthogonal click chemistry. Nanoscale. 2021.13,1813-1822. (IF: 8.307, 二区) (25) Tianhong Teng#, Ronggui Lin#, Ziguo Lin, Kun Ke, Xianchao Lin, Maoen Pan, Da Zhang*, Heguang Huang*, Photothermal augment stromal disrupting effects for enhanced Abraxane synergy chemotherapy in pancreatic cancer PDX mode. Biomaterials Science. 2020. 21, 8: 3278-3285. (IF: 7.590, 二区) (26) Da Zhang#, Ziguo Lin#, Shanyou Lan, Haiyan Sun*, Yongyi Zeng* Xiaolong Liu*. The Design of Janus Black Phosphorus Quantum dots@Metal-Organic Nanoparticles for Simultaneously Enhancing Environmental Stability and Photodynamic therapy Efficiency, Mater. Chem. Front., 2019, 3, 656-663. (IF: 8.4, 二区) (27) Da Zhang # , Xiao Lin# , Shanyou Lan# , Haiyan Sun, Xuandong Wang, Xiaolong Liu, Yun Zhang, and Yongyi Zeng*. Localized Surface Plasmon Resonance Enhanced Singlet Oxygen Generation and Light Absorption Based on Black Phosphorus@AuNPs Nanosheet for Tumor Photodynamic / Thermal Therapy. Particle&Particle Systems Characterization, 2018. 35, 1800010. (IF: 3.31, 三区) (28) Da Zhang, Ming Wu, Yongyi Zeng, Naishun Liao, Zhixiong Cai, Gang Liu, Xiaolong Liu*, Jingfeng Liu*.Lipid micelles packaged with semiconducting polymer dots as simultaneous MRI / photoacoustic imaging and photodynamic / photothermal dual-modal therapeutic agents for liver cancer. Journal of Materials Chemistry B, 2016. 4, 589-599. (IF: 6.331, 二区) (29) Zhixiong Cai#, Da Zhang#, Xinyi Lin, Yunzhu Chen, Ming Wu, Zuwu Wei, Zhenxi Zhang1, Xiaolong Liu5,2,3 and Cuiping Yao5,1 (2017). Glutathione responsive micelles incorporated with semiconducting polymer dots and doxorubicin for cancer photothermal-chemotherapy. Nanotechnology, 28(42), 425102. (30) 张达, 周非凡, 邢达. 功能化氧化石墨烯的靶向肿瘤成像与光热治疗. 科学通报, 2013; 7: 586-592.11 授权发明专利： (1) 张达;刘景丰;刘小龙;吴名,一种PEG修饰的二维纳米片光热转换材料及其应用.专利号ZL 201710655253.6； (2) 张达;刘小龙;吴名;刘景丰,肿瘤微酸性敏感的铜-药物共配位自组装纳米粒及应用.专利号ZL 201710102120.6； (3) 张达;刘景丰;刘小龙;曾永毅,一种光敏纳米复合物及其制备方法和应用.专利号ZL 201811343150.7； (4) 张达;曾永毅;刘景丰;刘小龙,黑磷量子点/铂杂化介孔二氧化硅纳米颗粒及制备方法和应用.专利号ZL 201811343125.9； (5) 刘景丰;刘小龙;黄爱民; 张达, 用于肝癌多模态影像和光热治疗的多功能纳米探针及应用.专利号ZL 201310695697.4； (6) 刘小龙;刘景丰; 张达;曾永毅, 用于肿瘤早期诊断与光学治疗的多功能纳米胶束及其应用. 专利号ZL 201510429203.7；（已转化，金额120万元,见附件）； (7) 刘小龙; 张达;郑友世;蔡志雄;苏小平.一种人工改造自然杀伤性细胞及其制备与应用.专利号201910324655.7； (8) 杨黄浩;李娟; 张达;刘小龙, 含有至少2个硫原子的杂环化合物在制备纳米疫苗中的应用及制得的纳米疫苗.专利号202010330996.8； (9) 郑友世;刘小龙; 张达;林自国. 一种核酸适体功能化NK细胞及其制备与应用.专利号202010530479.5； (10) 刘景丰;刘小龙;郑友世; 张达;曾永毅.一种增强NK细胞对肿瘤细胞靶向杀伤力的培养方法.专利号202010353458.0； (11) 吴名; 张达;刘小龙;刘景丰;曾永毅.用于声动力/气体协同抗肿瘤治疗的仿生纳米材料及其制备方法.专利号202010555452.1； (12) 杨黄浩;李娟;张达;刘小龙.APPLICATION OF HETEROCYCLIC COMPOUND CONTAINING AT LEAST TWO SULFUR ATOMS IN PREPARING NANO-VACCINE AND PREPARED NANO-VACCINE. PCT/CN2020 / 134162. |
